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ea0084ps1-05-42 | Miscellaneous | ETA2022

Not all automated FT4 immunoassays measure accurately in samples of pregnant women and hemodialysis patients

Jansen Heleen , van Herwaarden Antonius , Vervloet Marc , Painter Rebecca , Huijgen Henk , Hillebrand Jacquelien , Boelen Anita , Heijboer Annemieke

Objectives: Free thyroxine (fT4) measurements are performed to detect thyroid disorders and monitor treatment. FT4 is measured using automated immunoassays (IAs) which face established analytical challenges due to low serum concentrations in the picomolar range and the precarious equilibrium between free and bound T4 (to thyroid-binding globulin (TBG) and (pre-)albumin). Furthermore, IAs are known to be affected by the composition of the serum sample (matrix-effects), which ca...

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ea0099oc10.2 | Oral Communications 10: Calcium and Bone | Part II | ECE2024

The effect of gender affirming hormone therapy on calcium-phosphate homeostasis in transgender persons

Geels Raya , de Jongh Renate , van Velzen Daan , Vlot Mariska , Wiepjes Chantal , T' Sjoen Guy , Vervloet Marc , Heijboer Annemieke C , den Heijer Martin

Objective: The aim of the current study is to examine the effects of gender affirming hormone therapy in transgender persons on calcium and phosphate concentrations and their regulatory hormones.Design: A prospective cohort studyMethods: This study investigated changes in calcium and phosphate concentrations and their regulatory hormones in trans women and trans men during the first year of hormone therapy. Trans women received est...

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Endocrine Abstracts

Not all automated FT4 immunoassays measure accurately in samples of pregnant women and hemodialysis patients

The effect of gender affirming hormone therapy on calcium-phosphate homeostasis in transgender persons

BiosciAbstracts